Pre-emptive analgesia and the paravertebral space--an ignis fatuus

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Pre-emptive analgesia.

Transmission of pain signals evoked by tissue damage leads to sensitization of the peripheral and central pain pathways. Pre-emptive analgesia is a treatment that is initiated before the surgical procedure in order to reduce this sensitization. Owing to this 'protective' effect on the nociceptive system, pre-emptive analgesia has the potential to be more effective than a similar analgesic treat...

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Pre - Emptive Extradural Analgesia

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Vitreoretinal surgery: pre-emptive analgesia.

AIM Vitrectomies are performed either under general anesthesia (GA), local anesthesia (LA), or a combination of both. Postoperative pain is expected to be less in patients with LA because of prolonged action of the local anaesthetic. Pre-emptive analgesia is based on the idea that analgesia initiated before a nociceptive event will be more effective than analgesia commenced afterwards. The auth...

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Pre-emptive analgesia: importance of timing.

pain has been dominated by an outdated conceptualization of pain.1 Pain is viewed as the end-product of a passive transmission system that faithfully transmits a peripheral signal to the spinal cord and on up to a pain centre in the brain. This view has led to an approach of managing postoperative pain that does not provide adequate control of pain, in part, because it focuses on treating the p...

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Effectiveness of pre-emptive analgesia is unproven

Study Selection Studies were selected if they were randomised controlled trials (RCTs) that compared the outcome when analgesics were given before surgical incision with the outcome when the same medication was given after surgical incision. Studies that compared pre-emptive analgesia with no analgesia or that compared pre-emptive analgesia with pre-emptive analgesia plus analgesia given after ...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2006

ISSN: 0007-0912,1471-6771

DOI: 10.1093/bja/ael060